What is metopic synostosis? Hum Mol Genet. 2010 May 1. The records of 36 consecutive children with metopic synostosis followed at one craniofacial center from 1978 to 1993 were reviewed and parental questionnaires were completed to establish the frequency of mental retardation, learning disabilities, and behavioral problems associated with this synostosis. Children with metopic, unicoronal or lambdoid synostosis were much more likely to have a learning problem than children with the most common form of single-suture craniosynostosis – sagittal synostosis. The purpose of this study was twofold: first, to assess the degree of developmental, educational, and behavioral problems in patients with nonsyndromic trigonocephaly and second, to establish whether patients with mild degrees of trigonocephaly had a lower frequency of such problems. Metopic synostosis is presently the second most common form of craniosynostosis, accounting for 19% to 28% of cases 53–55 and having a prevalence of 0.9 to 2.3 per 10 000 live births. The use of sagittal springs with strip craniectomy may be recommended for sagittal synostosis if the child is younger than 5 months at the time of initial surgery. The metopic suture begins at the nose and continues superiorly to meet the sagittal suture. 2009 Sep. 20(5):1439-44. . This type affects the metopic suture, which runs from the top of the head down the middle of the forehead to the bridge of the nose. Surgical therapy for true metopic synostosis involves a fronto-orbital advancement which allows for widening the skull at the temporal fossa. Miraoui H, Ringe J, Haupl T, Marie PJ. Craniosynostosis is when one or more of the special seams (sutures) in a baby's skull close earlier than normal. J Craniofac Surg. The neurobehavioral morbidity of nonsyndromic trigonocephaly is incompletely understood. 19(9):1678-89. . Increased EFG- and PDGFalpha-receptor signaling by mutant FGF-receptor 2 contributes to osteoblast dysfunction in Apert craniosynostosis. Children with metopic, unicoronal and lambdoid synostosis tended to score lower on most measures than those with sagittal fusion (P<.001 to .82). This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of metopic craniosynostosis (also … Metopic craniosynostosis is a type of non-syndromic craniosynostosis that occurs when the metopic suture fuses before birth. ... Study how the condition affects learning and behavior; ... Fronto-orbital surgery for metopic and unilateral coronal synostosis. Object. Children with operated metopic synostosis performed significantly worse on measures of motor functioning (g w = −.45), visuospatial skills (g w = −.32), attention (g w = −.50), executive functioning (g w = −.36), arithmetic ability (g w = −.37), and behavior (g w = −.34). This corrects the abnormal triangular shape of the forehead and increases the intracranial space in the anterior fossa. Treatment involves releasing the suture and expanding and rounding out the upper face, forehead and skull. Metopic craniosynostosis. Also known as cranial spring surgery. Variations of endoscopic and open repair of metopic craniosynostosis. Metopic craniosynostosis results in a narrow, triangular forehead with pinching of the temples laterally. Continues superiorly to meet the sagittal suture Apert craniosynostosis in the anterior fossa learning and behavior ;... Fronto-orbital for! ;... 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